Is Armodafinil a Controlled Substance

What is the Difference Between Waklert, Armodafinil, and Modafinil is Armodafinil a Controlled Substance

Armodafinil is used to treat narcolepsy, obstructive sleep apnea (also called hypopnea syndrome), and shift work disorder. It does not cure these conditions.

Store this medication in a safe place where others cannot get it accidentally or on purpose. Keep track of how many tablets are left so you know if any are missing.

Armodafinil : Treatment of sleep apnea

Often prescribed off-label to treat narcolepsy, this drug can help reduce daytime sleepiness in patients with obstructive sleep apnea. Although this medication decreases sleepiness, it is not a cure for sleep apnea and it should be taken as directed by your doctor. It can cause serious side effects, such as a fast/pounding heartbeat or mental changes, so you should tell your doctor immediately if you notice these symptoms. You should also continue to use your CPAP machine and any other sleep apnea treatments you have been prescribed unless told otherwise by your doctor.

This wakefulness-promoting medicine is a dopamine agonist and a methylphenidate reuptake inhibitor. It acts on the hypothalamus in the brain to increase dopamine and other neurotransmitters that promote wakefulness. It is a close relative of modafinil and has been shown to have similar pharmacokinetics but with higher plasma concentrations later in the day.

In a 12-week double-blind study of patients with excessive sleepiness associated with treated obstructive sleep apnea, shift work disorder, or narcolepsy, armodafinil significantly improved wakefulness as measured by the MWT at all visits compared with placebo. These improvements were sustained during the 12 weeks of treatment. In addition, armodafinil reduced patient-reported fatigue and the extent to which ES interfered with daily functioning, such as the number of naps and unintended sleep episodes.


The dosage of this medication varies from person to person and should be determined by your doctor. The usual dose is 150 to 250 mg taken once a day in the morning. It can be taken with or without food. This medicine may cause dizziness, stomach upset, headache, tremors, dilated pupils, and nervousness. It is important to follow your doctor’s instructions carefully.

Armodafinil 150 is a central nervous system stimulant that promotes wakefulness and improves attention and cognitive function. It helps people with narcolepsy, obstructive sleep apnea (also called hypopnea syndrome), or shift work sleep disorder stay awake during the day. It works by changing the way your brain responds to certain chemicals that control sleepiness. This medicine is available only with a prescription from your doctor.

This medicine interacts with a number of drugs. You should tell your doctor if you are taking any other medications, including over-the-counter medicines and herbal supplements. It also interacts with clopidogrel, a drug that prevents blood clots from forming. This interaction may reduce the effectiveness of clopidogrel.

This medication should be stored at room temperature. It should be kept out of the reach of children. If you stop taking this medication, you will experience withdrawal symptoms such as shaking, sweating, chills, nausea, and confusion. If you have serious symptoms, you should seek medical care.

Side effects

Armodafinil reduces extreme sleepiness in people with narcolepsy. It also helps to keep people awake during scheduled waking hours when they have shift work disorder (SWD). It is in a class of medications called wakefulness-promoting agents. This medication may cause serious skin reactions. Get emergency medical help if you have signs of a severe reaction to armodafinil or similar medications. These include fever, swollen glands, mouth or throat sores, a red or purple skin rash that spreads and causes blistering and peeling, and trouble breathing.

In clinical trials, armodafinil improved wakefulness compared with placebo in people with OSA and narcolepsy. It reduced the mean ESS score by about 8 to 16 points. The improvement was maintained at all follow-up visits.

The effectiveness of this medication for other uses has not been established. Do not take this medicine to treat other conditions unless your doctor tells you to. This medication should not be used by children under 17 years old. It is not known if this medicine passes into breast milk. Do not breastfeed while taking it.

If you have a history of heart disease, chest pain, or a problem with your blood pressure or liver, you should not use this medication. This drug can affect your blood pressure and cause you to sweat more. Also tell your doctor if you have had any other type of allergic reaction to drugs or foods, or any mental/mood disorders such as depression, mania, or psychosis.


The information provided on this site is intended to supplement, not substitute for, the expertise and judgment of your doctor or other health care professional. It is not intended to cover all possible uses, directions, precautions, or adverse effects.

Armodafinil may cause some people to be agitated or irritable. This drug may also increase your blood pressure and heart rate. Do not drive or take other dangerous tasks until you know how this medication affects you. This medication can affect your reaction time and concentration. Avoid consuming alcohol, other drugs that can slow your actions (such as street drugs or prescription medicine), and foods such as chocolate or tea with caffeine while taking this medication.

This medication should not be used during pregnancy. It is unknown if this drug passes into breast milk. Ask your doctor before breastfeeding.

Do not stop using this medication unless your doctor tells you to. This drug may cause withdrawal in some people. You should lower your dose gradually to reduce the risk of withdrawal. If withdrawal symptoms occur, get medical help right away.

This medication may interfere with certain lab tests, including urinalysis and liver function tests. Inform your doctor if you are pregnant or plan to become pregnant, or if you have an infection, heart disease, high blood pressure, depression or other mental illness, or a history of substance abuse. Store this medication at room temperature and keep it out of the reach of children.